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I am in _______charge of the class which was in __________charge of my wife.

  A. 不填；the　　B. 不填；不填  C. the; 不填　　　D. the; the

A


解析:

in charge of 的意思是“負(fù)責(zé)”、“管理”，其主語(yǔ)通常是人；in the charge of 的意思是“由……負(fù)責(zé)或管理”，其主語(yǔ)通常是物。

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